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ZBTB33 Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00€ - 410.00€
Spécification
Antigène | ZBTB33 |
---|---|
Concentration | 0.43 mg/mL |
Applications | Western Blot, Immunoprecipitation |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
---|---|---|---|---|---|---|---|---|---|
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16856765
|
Proteintech
55270-1-AP-20UL |
20 μL |
145.00€
20µL |
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16846765
|
Proteintech
55270-1-AP-150UL |
150 μL |
410.00€
150µL |
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Description
ZAP70, a 70 kDa member of the Syk tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Upon T cell antigen receptor (TCR) engagement, ZAP70 is phosphorylated on tyrosines 292, 315 and 319 in the interdomain B, located between the SH2 and kinase domains. Phosphorylation of both tyrosines 315 (a Vav binding site) and 319 (a Lck binding site) enhances ZAP70 function in mediating lymphocyte signaling, while tyrosine 292 terminates the transient activation of ZAP70 and attentuates lymphocyte signaling.Spécification
ZBTB33 | |
Western Blot, Immunoprecipitation | |
Unconjugated | |
Rabbit | |
Human | |
Q86T24 | |
10009 | |
Peptide | |
Primary | |
-20°C | |
ZBTB33 |
0.43 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
KAISO, ZBTB33, ZNF kaiso, ZNF348 | |
ZBTB33 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |