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UNC13A/Munc13-1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 55053-1-AP-20UL
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Description
The antibody is specific to UNC13A.
UNC13A, also named as KIAA1032, belongs to the unc-13 family. It plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. UNC13A is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses. UNC13A is also involved in secretory granule priming in insulin secretion.Spécification
UNC13A/Munc13-1 | |
Polyclonal | |
Unconjugated | |
UNC13A | |
KIAA1032, Munc13 1, Protein unc 13 homolog A, unc 13 homolog A (C. elegans), UNC13A | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
23025, 382018 | |
-20°C | |
Liquid |
Western Blot, Immunoprecipitation | |
0.33 mg/mL | |
0.1 M glycine, 0.1 M sodium bicarbonate with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q4KUS2, Q9UPW8 | |
Unc13a | |
Peptide | |
20 μL | |
Primary | |
Mouse, Human | |
Antibody | |
IgG |