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TCIRG1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 12649-1-AP-20UL
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Description
The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.Spécification
| TCIRG1 | |
| Polyclonal | |
| Unconjugated | |
| TCIRG1 | |
| a3, Atp6i, ATP6N1C, ATP6V0A3, OC 116 kDa, OC 116kDa, OC116, OPTB1, Stv1, T cell immune regulator 1, TCIRG1, TIRC7, V ATPase 116 kDa isoform a3, Vph1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 10312, 27060, 293650 | |
| -20°C | |
| Liquid |
| Immunofluorescence, Immunocytochemistry, Western Blot | |
| 0.19 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| Q13488 | |
| TCIRG1 | |
| TCIRG1 Fusion Protein Ag3378 | |
| 20 μL | |
| Primary | |
| Human, Rat, Mouse | |
| Antibody | |
| IgG |