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Thermo Scientific Chemicals SB 225002
Description
SB 225002 is a selective non-peptide CXCR2 inhibitor which suppresses IL-8 induced neutrophil chemotaxis and margination. In addition, SB 225002 reduces MPO activity, IL-1β, MIP-2, and keratinocyte-derived chemokine (KC) levels. Further studies suggest that SB 225002 decreases the expression of vascular endothelial growth factor, inducible NOS (NO synthase), and Cox-2 (cyclooxygenase-2 proteins) in colon tissue.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Spécification
Spécification
| Quantité | 5 mg |
| Description | Jaune |
| Contenu et stockage | -30°C à -10°C |
| À utiliser avec (application) | Puissant antagoniste sélectif et compétitif du récepteur couplé aux protéines G CXCR 2 |
| Poids de la formule | 352,10g/mol |
| Sensibilité | Sensible à l’humidité |
| Solubilité | Soluble à 100 mM dans le DMSO et à 50 mM dans l’éthanol |
| Type de produit | Signal Transduction Reagent |
| Forme | Solide |
RUO – Research Use Only