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REST Rabbit anti-Human, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 22242-1-AP-150UL
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Description
Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.Spécification
| REST | |
| Polyclonal | |
| Unconjugated | |
| REST | |
| NRSF, REST, X2 box repressor, XBR | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 5978, 83618 | |
| -20°C | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 0.4 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| O54963, Q13127 | |
| REST | |
| REST Fusion Protein Ag17707 | |
| 150 μL | |
| Primary | |
| Human, Rat | |
| Antibody | |
| IgG |