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RAB5A Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
145.00€ - 410.00€
Spécification
Antigène | RAB5A |
---|---|
Concentration | 0.22 mg/mL |
Applications | Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunocytochemistry |
Classification | Polyclonal |
Conjugué | Unconjugated |
Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
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Code produit | Marque | Quantité | Prix | Quantité et disponibilité | |||||
16879744
|
Proteintech
20228-1-AP-20UL |
20 μL |
145.00€
20µL |
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16869744
|
Proteintech
20228-1-AP-150UL |
150 μL |
410.00€
150µL |
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Description
The antibody is specific to RAB5A. It has no cross reaction to RAB5B or RAB5C.
RAB5 are among the small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB5A is required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension. Required for the exosomal release of SDCBP, CD63, PDCD6IP and syndecan. Regulates maturation of apoptotic cell-containing phagosomes, probably downstream of DYN2 and PIK3C3.Spécification
RAB5A | |
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Immunocytochemistry | |
Unconjugated | |
Rabbit | |
Mouse, Human | |
P20339, Q9CQD1 | |
271457, 5868 | |
Peptide | |
Primary | |
-20°C | |
RAB5A |
0.22 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
RAB5, RAB5A, Ras related protein Rab 5A | |
Rab5a | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |