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Phospho-AKT (Ser473) Mouse anti-Human, Mouse, Clone: 1C10B8, Proteintech
Mouse Monoclonal Antibody
Marque: Proteintech 66444-1-IG-20UL
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Description
This antibody detects all the members of AKT with phospho-modification at Ser473.
The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.Spécification
| Phospho-AKT (Ser473) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P31749, P31750 | |
| AKT1 | |
| Peptide | |
| 20 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG1 |
| Immunohistochemistry (Paraffin), Western Blot | |
| 1C10B8 | |
| Unconjugated | |
| AKT1 | |
| AKT, AKT1, AKT1-phospho-S473, pakt, p-AKT, Phospho akt, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha | |
| Mouse | |
| Protein G | |
| RUO | |
| 11651, 207 | |
| -20°C | |
| Liquid |