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MPP5 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 17710-1-AP-20UL
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Description
Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Spécification
MPP5 | |
Polyclonal | |
Unconjugated | |
MPP5 | |
MAGUK p55 subfamily member 5, MPP5, PALS1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
314259, 56217, 64398 | |
-20°C | |
Liquid |
Western Blot, Immunoprecipitation | |
0.18 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q8N3R9, Q9JLB2 | |
Mpp5 | |
MPP5 Fusion Protein Ag12010 | |
20 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |