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JAML Rabbit anti-Human, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Marque: Proteintech 21302-1-AP-20UL
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Description
AMICA transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.Spécification
JAML | |
Polyclonal | |
Unconjugated | |
JAML | |
AMICA, AMICA1, CREA7 1, CREA7 4, Gm638, JAML | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
120425 | |
-20°C | |
Liquid |
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunofluorescence, Western Blot, Flow Cytometry | |
0.33 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q86YT9 | |
JAML | |
JAML Fusion Protein Ag15900 | |
20 μL | |
Primary | |
Human | |
Antibody | |
IgG |